Jonathan Graf, MD

Education
M.D., 1997 - School of Medicine, University of Pennsylvania
Residency, - School of Medicine - Internal Medicine, University of California, San Francisco
Websites
Publications

  1. Deane KD, Striebich CC, Feser ML, O'Dell JR, James JA, Sparks JA, Davis JM, Graf J, McMahon MA, Solow EB, Forbess L, Tiliakos A, Schiopu E, Danila MI, Horowitz DL, Kay J, Strickland CD, Guthridge JM, Arriens C, Grossman JM, Demoruelle MK, Bemis EA, Frazer-Abel A, Fleischer CL, Fox DA, Mikuls TR, Greenleaf M, York K, Walker S, Keyes-Elstein L, Byron M, Fedler J, Goldmuntz EA, Holers VM. A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis. Arthritis & rheumatology (Hoboken, N.J.) 2025. PMID: 40884017


  2. Adams C, Nair N, Plant D, Verstappen SMM, Quach HL, Quach DL, Carvidi A, Nititham J, Nakamura M, Graf J, Barton A, Criswell LA, Barcellos LF. Identification of cell-specific differential DNA methylation associated with methotrexate treatment response in rheumatoid arthritis. Arthritis & rheumatology (Hoboken, N.J.) 2023. PMID: 36716083


  3. Baker R, Mantilla B, Graf J, Katz PP, Goglin S, Barton JL, Liew JW, Wysham KD. Racial and Ethnic Differences in a Biochemical Marker of Rheumatoid Arthritis Disease Activity. ACR Open Rheumatology 2023. PMID: 36754575


  4. Strait A, Graf J, Margaretten M, Yazdany J, Goglin S. Race, Ethnicity and Disparities in Rheumatology Educational Materials. Arthritis care & research 2021. PMID: 33768717


  5. Wysham KD, Shofer J, Lui G, Trupin L, Andrews JS, Black DM, Graf J, Shoback DM, Katz PP. Low cumulative disease activity is associated with higher bone mineral density in a majority Latinx and Asian US rheumatoid arthritis cohort. A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 2022. PMID: 35152085


  6. Meednu N, Barnard J, Callahan K, Coca A, Marston B, Thiele R, Tabechian D, Bolster M, Curtis J, Mackay M, Graf J, Keating R, Smith E, Boyle K, Keyes-Elstein L, Welch B, Goldmuntz E, Anolik JH. Activated peripheral blood B cells in rheumatoid arthritis and relationship to anti-TNF treatment and response: randomized clinical trial for anti-TNF effects on B cells. Arthritis & rheumatology (Hoboken, N.J.) 2021. PMID: 34347945


  7. G. Lui, E. Noss, N. Singh, J. Andrews, J. Graf, K. Wysham. POS0459 UNSUPERVISED CLUSTERING IDENTIFIES UNIQUE SUBSETS OF PATIENTS IN A RACIALLY AND ETHNICALLY DIVERSE RHEUMATOID ARTHRITIS COHORT. Annals of the rheumatic diseases 2021. PMID:


  8. . Glucocorticoids and B Cell Depleting Agents Substantially Impair Immunogenicity of mRNA Vaccines to SARS-CoV-2. medRxiv : the preprint server for health sciences 2021. PMID: 33851176


  9. Gianfrancesco MA, McCulloch CE, Trupin L, Graf J, Schmajuk G, Yazdany J. Reweighting to address nonparticipation and missing data bias in a longitudinal electronic health record study. Annals of epidemiology 2020. PMID: 32807591


  10. Kenji Mamoto, Tomohiro Shimizu, Matthew Tanaka, Valentina Pedoia, Andrew Burghardt, Ursula Heilmeier, Thomas Link, Jonathan Graf, John Imboden, LI Xiaojuan. THU0067 THREE-MONTH RADIOLOGICAL CHANGES IN WRIST JOINT MEASURED BY MRI AND HR-PQCT CAN PREDICT 12-MONTH CHANGES IN EROSION AND FUNCTIONAL OUTCOMES AFTER MTX AND ANTI-TNF TREATMENT IN PATIENTS WITH RHEUMATOID ARTHRITIS: A MULTI-MODALITY IMAGING STUDY. Poster Presentations 2019. PMID:


  11. Shimizu T, Cruz A, Tanaka M, Mamoto K, Pedoia V, Burghardt AJ, Heilmeier U, Link TM, Graf J, Imboden JB, Li X. Structural Changes over a Short Period Are Associated with Functional Assessments in Rheumatoid Arthritis. The Journal of rheumatology 2019. PMID: 30770506


  12. Graf J, Imboden J. Vasculitis and peripheral neuropathy. Current opinion in rheumatology 2019. PMID: 30461543


  13. Gianfrancesco MA, Trupin L, Shiboski S, van der Laan M, Graf J, Imboden J, Yazdany J, Schmajuk G. Smoking Is Associated with Higher Disease Activity in Rheumatoid Arthritis: A Longitudinal Study Controlling for Time-varying Covariates. The Journal of rheumatology 2018. PMID: 30504507


  14. J. Graf, B. Abbruzzese, F. Cope, S. Behr, J. Sanders, A. Kissling, D. Ralph, J. Shuping, M. Blue, C. Hartings, R. Hershey, H. Bailey, A. spaulding, M. haynam, A. Ismail. AB0248 Evaluation of subcutaneously (SC) injected tc 99m tilmanocept localization in active rheumatoid arthritis (RA) subjects by planar and spect/ct. Annals of the rheumatic diseases 2018. PMID:


  15. Mok A, Rhead B, Holingue C, Shao X, Quach HL, Quach D, Sinclair E, Graf J, Imboden J, Link T, Harrison R, Chernitskiy V, Barcellos LF, Criswell LA. Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients. Volume 70 of Issue 4. Arthritis & rheumatology (Hoboken, N.J.) 2018. PMID: 29287311


  16. Goglin SE, Manesh R, Graf JD. A 56-Year-Old Man With Visual Changes and Arthralgias. Volume 70 of Issue 1. Arthritis care & research 2018. PMID: 29088577


  18. Graf J. Central Nervous System Manifestations of Antiphospholipid Syndrome. Volume 43 of Issue 4. 2017. PMID: 29061241


  19. Shimizu T, Choi HJ, Heilmeier U, Tanaka M, Burghardt AJ, Gong J, Chanchek N, Link TM, Graf J, Imboden JB, Li X. Assessment of 3-month changes in bone microstructure under anti-TNFa therapy in patients with rheumatoid arthritis using high-resolution peripheral quantitative computed tomography (HR-pQCT). Volume 19 of Issue 1. 2017. PMID: 28978352


  20. T Shimizu, HJ Choi, U Heilmeier, M Tanaka, AJ Burghardt, J Gong, N Chanchek, TM Link, J Graf, JB Imboden, X Li. OP0020 Assessment of 3-month changes in bone microstructure under anti-tnfa therapy in patients with rheumatoid arthritis using hr-pqct. Annals of the rheumatic diseases 2017. PMID:


  21. Carmona-Rivera C, Purmalek MM, Moore E, Waldman M, Walter PJ, Garraffo HM, Phillips KA, Preston KL, Graf J, Kaplan MJ, Grayson PC. A role for muscarinic receptors in neutrophil extracellular trap formation and levamisole-induced autoimmunity. JCI insight 2017. PMID: 28194438


  22. Ku E, Pedoia V, Tanaka M, Heilmeier U, Imboden J, Graf J, Link T, Li X. Evaluating radiocarpal cartilage matrix changes 3-months after anti-TNF treatment for rheumatoid arthritis using MR T1? imaging. Volume 45 of Issue 5. Journal of magnetic resonance imaging : JMRI 2016. PMID: 27661002


  23. P.C. Grayson, C. Carmona-Rivera, J. Graf, J. Irizarry-Caro, K. Phillips, K. Preston, M. Purmalek, V. Subramaniam, P. Thompson, M. Waldman, M.J. Kaplan. OP0054 Neuroimmunomodulation of Neutrophils as A Novel Mechanism of Levamisole-Induced Vasculitis. Annals of the rheumatic diseases 2016. PMID:


  25. Scheibe MM, Imboden JB, Schmajuk G, Margaretten M, Graf JD, Chen AH, Yelin EH, Yazdany J. Efficiency Gains for Rheumatology Consultation Using a Novel Electronic Referral System in a Safety-Net Health Setting. Volume 67 of Issue 8. Arthritis care & research 2015. PMID: 25623810


  26. Hsue PY, Scherzer R, Grunfeld C, Imboden J, Wu Y, Del Puerto G, Nitta E, Shigenaga J, Schnell Heringer A, Ganz P, Graf J. Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. Volume 3 of Issue 5. 2014. PMID: 25336464


  27. Carlson AQ, Tuot DS, Jen KY, Butcher B, Graf J, Sam R, Imboden JB. Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. Volume 93 of Issue 17. 2014. PMID: 25398064


  28. Coffey G, Betz A, Graf J, Stephens G, Hua Lin P, Imboden J, Sinha U. Methotrexate and a spleen tyrosine kinase inhibitor cooperate to inhibit responses to peripheral blood B cells in rheumatoid arthritis. Volume 1 of Issue 2. 2013. PMID: 25505569


  29. Belani H, Gensler L, Bajpai U, Meinhardt E, Graf J, Pincus L, Leslie KS. Neutrophilic urticaria with systemic inflammation: a case series. Volume 149 of Issue 4. JAMA dermatology 2013. PMID: 23715523


  30. Richman NC, Yazdany J, Graf J, Chernitskiy V, Imboden JB. Extraarticular manifestations of rheumatoid arthritis in a multiethnic cohort of predominantly Hispanic and Asian patients. Volume 92 of Issue 2. Medicine 2013. PMID: 23429352


  31. Barton JL, Schmajuk G, Trupin L, Graf J, Imboden J, Yelin EH, Schillinger D. Poor knowledge of methotrexate associated with older age and limited English-language proficiency in a diverse rheumatoid arthritis cohort. Volume 15 of Issue 5. Arthritis research & therapy 2013. PMID: 24432366


  32. Graf J. Rheumatic manifestations of cocaine use. Volume 25 of Issue 1. 2013. PMID: 23196324


  33. Bajpai UD, Swainson LA, Mold JE, Graf JD, Imboden JB, McCune JM. A functional variant in FCRL3 is associated with higher Fc receptor-like 3 expression on T cell subsets and rheumatoid arthritis disease activity. Volume 64 of Issue 8. Arthritis and rheumatism 2012. PMID: 22392608


  34. Priscilla Hsue, Carl Grunfeld, John Imboden, Yuaner Wu, Rebecca Scherzer, Saira Mohammed, Gus del Puerto, Amanda Schnell Heringer, Peter Ganz, Jonathan Graf. DEPLETION OF B-CELLS WITH RITUXIMAB IMPROVES ENDOTHELIAL FUNCTION AND REDUCES INFLAMMATION AMONG INDIVIDUALS WITH RHEUMATOID ARTHRITIS. Journal of the American College of Cardiology 2012. PMID:


  35. Graf J, Lynch K, Yeh CL, Tarter L, Richman N, Nguyen T, Kral A, Dominy S, Imboden J. Purpura, cutaneous necrosis, and antineutrophil cytoplasmic antibodies associated with levamisole-adulterated cocaine. Volume 63 of Issue 12. Arthritis and rheumatism 2011. PMID: 22127712


  36. Lynch KL, Dominy SS, Graf J, Kral AH. Detection of levamisole exposure in cocaine users by liquid chromatography-tandem mass spectrometry. Volume 35 of Issue 3. 2011. PMID: 21439154


  37. Rooney T, Scherzer R, Shigenaga JK, Graf J, Imboden JB, Grunfeld C. Levels of plasma fibrinogen are elevated in well-controlled rheumatoid arthritis. Volume 50 of Issue 8. 2011. PMID: 21441551


  39. Barton JL, Imboden J, Graf J, Glidden D, Yelin EH, Schillinger D. Patient-physician discordance in assessments of global disease severity in rheumatoid arthritis. Volume 62 of Issue 6. Arthritis care & research 2010. PMID: 20535797


  40. Graf J, Scherzer R, Grunfeld C, Imboden J. Levels of C-reactive protein associated with high and very high cardiovascular risk are prevalent in patients with rheumatoid arthritis. Volume 4 of Issue 7. PloS one 2009. PMID: 19606218