The Journal of experimental medicine
Cbl-b deficiency prevents functional but not phenotypic T cell anergy.
The BAFFling persistence of memory B cells.
Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness.
Human LAT mutation results in immune deficiency and autoimmunity but also raises questions about signaling pathways.
A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70.
A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity.
B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency.
A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.
Distinct roles for Syk and ZAP-70 during early thymocyte development.
Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4.
