Proceedings of the National Academy of Sciences of the United States of America
Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells.
Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner.
Monoclonal antibody-mediated neutralization of SARS-CoV-2 in an IRF9-deficient child.
HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry.
Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis.
Origin of the sharp boundary that discriminates positive and negative selection of thymocytes.
Differential impact of the CD45 juxtamembrane wedge on central and peripheral T cell receptor responses.
Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival.
An extracatalytic function of CD45 in B cells is mediated by CD22.
The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase.