Proceedings of the National Academy of Sciences of the United States of America
Immune function in mice lacking the perforin gene.
Tumorigenesis mediated by an antigen receptor.
The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein.
Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.
Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.
Ligand-induced association between the T-cell antigen receptor and two glycoproteins.
At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor.
Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.
Inositol trisphosphate is generated by a rat natural killer cell tumor in response to target cells or to crosslinked monoclonal antibody OX-34: possible signaling role for the OX-34 determinant during activation by target cells.
Cholera toxin inhibits the T-cell antigen receptor-mediated increases in inositol trisphosphate and cytoplasmic free calcium.
