Andrew Gross, MD


I am the Rheumatology Clinic Chief at UCSF. I am responsible for all aspects of rheumatology clinical and teaching activities. I am committed to comprehensively aligning the rheumatology clinical program for ongoing success in all three of the traditional domains of academic medicine – clinical care, research and education.

I am co-director of the UCSF Scleroderma Center. I also work closely with the physicians in the UCSF Interstitial Lung Disease Program. My efforts are focused on providing multi-disciplinary, comprehensive care to patients with these complex conditions through a team based approach.

I am committed to:

1. Delivery of World Class Patient Care. UCSF Rheumatology continues to be recognized by "US News & World Report" as one of the 10 best hospitals in rheumatology.

2. Delivering outstanding training and education programs in rheumatic disease for rheumatology fellows, internal medicine residents and medical students. I work closely with the Rheumatology Fellowship Program Director to coordinate the one of the premier fellowships in rheumatology training. The program includes bedside teaching, post-clinic conferences, and a comprehensive didactic teaching program.

3. Fostering research in rheumatic disease. I see academic medical centers as the champions of research efforts that help us to better understand the causes of autoimmune disease. I focus my research efforts on collaborating with basic scientists on "translational" research efforts that help us understand the causes of disease in people. In addition, I continue to work with my rheumatology colleagues to develop new strategies that improve the delivery of care to rheumatology patients.
2018 - Diversity, Equity, and Inclusion Champion Training, University of California
M.D., 05/1996 - Medicine, Tufts University School of Medicine
B.S., 05/1991 - Biology, Bates College
  1. Gutierrez RA, Connolly K, Gross A, Haemel A. Transient dermatomyositis-like reaction following COVID-19 messenger RNA vaccination. JAAD case reports 2023. PMID: 37366492

  2. Rychkov D, Neely J, Oskotsky T, Yu S, Perlmutter N, Nititham J, Carvidi A, Krueger M, Gross A, Criswell LA, Ashouri JF, Sirota M. Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis. Frontiers in immunology 2021. PMID: 34177888

  3. Lalaoui N, Boyden SE, Oda H, Wood GM, Stone DL, Chau D, Liu L, Stoffels M, Kratina T, Lawlor KE, Zaal KJM, Hoffmann PM, Etemadi N, Shield-Artin K, Biben C, Tsai WL, Blake MD, Kuehn HS, Yang D, Anderton H, Silke N, Wachsmuth L, Zheng L, Moura NS, Beck DB, Gutierrez-Cruz G, Ombrello AK, Pinto-Patarroyo GP, Kueh AJ, Herold MJ, Hall C, Wang H, Chae JJ, Dmitrieva NI, McKenzie M, Light A, Barham BK, Jones A, Romeo TM, Zhou Q, Aksentijevich I, Mullikin JC, Gross AJ, Shum AK, Hawkins ED, Masters SL, Lenardo MJ, Boehm M, Rosenzweig SD, Pasparakis M, Voss AK, Gadina M, Kastner DL, Silke J. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease. Nature 2019. PMID: 31827281

  4. Juge PA, Lee JS, Ebstein E, Furukawa H, Dobrinskikh E, Gazal S, Kannengiesser C, Ottaviani S, Oka S, Tohma S, Tsuchiya N, Rojas-Serrano J, González-Pérez MI, Mejía M, Buendía-Roldán I, Falfán-Valencia R, Ambrocio-Ortiz E, Manali E, Papiris SA, Karageorgas T, Boumpas D, Antoniou K, van Moorsel CHM, van der Vis J, de Man YA, Grutters JC, Wang Y, Borie R, Wemeau-Stervinou L, Wallaert B, Flipo RM, Nunes H, Valeyre D, Saidenberg-Kermanac'h N, Boissier MC, Marchand-Adam S, Frazier A, Richette P, Allanore Y, Sibilia J, Dromer C, Richez C, Schaeverbeke T, Lioté H, Thabut G, Nathan N, Amselem S, Soubrier M, Cottin V, Clément A, Deane K, Walts AD, Fingerlin T, Fischer A, Ryu JH, Matteson EL, Niewold TB, Assayag D, Gross A, Wolters P, Schwarz MI, Holers M, Solomon JJ, Doyle T, Rosas IO, Blauwendraat C, Nalls MA, Debray MP, Boileau C, Crestani B, Schwartz DA, Dieudé P. MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease. The New England journal of medicine 2018. PMID: 30345907

  5. Kushner T, Shinkai K, Fox L, Ying D, Gross A, Balitzer D, Gill R, Brandman D. New presentation of autoimmune hepatitis with erythema multiforme. Hepatology (Baltimore, Md.) 2018. PMID: 29059460

  6. Saeed L, Schmidt TH, Gensler LS, Gross AJ, Fox LP, Scharschmidt TC, Gaensler K, Naik H, Rosenblum MA, Shinkai K. Successful treatment of mucous membrane pemphigoid with bortezomib. JAAD case reports 2017. PMID: 29387757

  7. Jiang B, Patino MM, Gross AJ, Leong SPL, Moretto JC, Kashani-Sabet M, Kim KB. Diffuse granulomatous panniculitis associated with anti PD-1 antibody therapy. JAAD case reports 2017. PMID: 29296642

  8. Kidambi TD, Schmajuk G, Gross AJ, Ostroff JW, Terdiman JP, Lee JK. Endoscopy is of low yield in the identification of gastrointestinal neoplasia in patients with dermatomyositis: A cross-sectional study. World journal of gastroenterology 2017. PMID: 28765700

  9. Morisset J, Vittinghoff E, Lee BY, Tonelli R, Hu X, Elicker BM, Ryu JH, Jones KD, Cerri S, Manfredi A, Sebastiani M, Gross AJ, Ley B, Wolters PJ, King TE, Kim DS, Collard HR, Lee JS. The performance of the GAP model in patients with rheumatoid arthritis associated interstitial lung disease. Respiratory medicine 2017. PMID: 28502419

  10. Gonzales JA, Haemel A, Gross AJ, Acharya NR. Management of Uveitis and Scleritis in Necrobiotic Xanthogranuloma. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2017. PMID: 28394239

  11. Wahl E, Gross A, Chernitskiy V, Trupin L, Gensler L, Chaganti K, Michaud K, Katz P, Yazdany J. Validity and Responsiveness of a 10-Item Patient-Reported Measure of Physical Function in a Rheumatoid Arthritis Clinic Population. Volume 69 of Issue 3. 2017. PMID: 27332620

  12. Chou A, Schulman JM, Gross AJ, Jordan RC, Ramos DM. Gingival pustules and sterile diffuse sclerosing osteomyelitis as a feature of synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome. Oral surgery, oral medicine, oral pathology and oral radiology 2015. PMID: 26619759

  13. Hua Z, Gross AJ, Lamagna C, Ramos-Hernández N, Scapini P, Ji M, Shao H, Lowell CA, Hou B, DeFranco AL. Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice. Journal of immunology (Baltimore, Md. : 1950) 2013. PMID: 24379120

  14. Wang W, Wang ZJ, Webb EM, Westphalen AC, Gross AJ, Yeh BM. Omental infarction preceded by anatomically upturned omentum. Clinical imaging 2013. PMID: 23932388

  15. Bucknor MD, Gross AJ, Link TM. Voriconazole-induced periostitis in two post-transplant patients. Journal of radiology case reports 2013. PMID: 24421948

  16. Shahaf G, Gross AJ, Sternberg-Simon M, Kaplan D, DeFranco AL, Mehr R. Lyn deficiency affects B-cell maturation as well as survival. European journal of immunology 2011. PMID: 22057631

  17. Gross AJ, Proekt I, DeFranco AL. Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells. European journal of immunology 2011. PMID: 21928281

  18. Gross AJ, Lyandres JR, Panigrahi AK, Prak ET, DeFranco AL. Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance. Journal of immunology (Baltimore, Md. : 1950) 2009. PMID: 19380785

  19. Gillis JZ, Dall'era M, Gross A, Yazdany J, Davis J. Six refractory lupus patients treated with rituximab: a case series. Volume 57 of Issue 3. Arthritis and rheumatism 2007. PMID: 17394185

  20. Gross AJ, Hochberg D, Rand WM, Thorley-Lawson DA. EBV and systemic lupus erythematosus: a new perspective. Journal of immunology (Baltimore, Md. : 1950) 2005. PMID: 15905498

  21. Thorley-Lawson DA, Gross A. Persistence of the Epstein-Barr virus and the origins of associated lymphomas. The New England journal of medicine 2004. PMID: 15044644