Arthur Weiss, MD, PhD

Education
2022 - Diversity, Equity, and Inclusion Champion Training, University of California
MD, PhD, 1979 - Immunology, Pritzker School of Medicine, University of Chicago
Residency, - Rheumatology, University of California, San Francisco
Honors and Awards
  • W.B. Coley Award, Cancer Research Institute, 2019
  • Eberly Lecture, U. Pittsburgh, 2019
  • Establishment of Arthur Weiss Lectureship in Rheumatology and Immunology, UCSF, 2019
  • Associate Member, European Molecular Biology Organization, 2017
  • Ephraim P. Engleman Memorial Lecture, American College of Rheumatology, 2016
  • Merit Award, NIH, NIAID, 2016
  • Frank and Shirley Fitch Lecture, University of Chicago, 2016
  • Lifetime Achievement Award, American Association of Immunologists, 2012
  • Lifetime Achievement in Mentoring Award, UCSF, 2012
  • Distinguished Investigator Award, American College of Rheumatology, 2004
  • Member, National Academy of Medicine, 2004
  • Member, National Academy of Sciences, 2004
  • Fellow, American Academy of Arts and Sciences, 2003
  • American Association of Immunologists-Huang Foundation Meritorious Career Award, American Association of Immunologists, 2001
  • Forty-first Faculty Research Lecturer, UCSF, 1998
  • Lee C. Howley Prize, Arthritis Foundation, 1997
  • Junior Investigator Award, American Association of Immunologists, 1993
  • Henry Kunkel Young Investigator Award, American College of Rheumatology, 1990
Websites
Publications

  1. McCarthy EE, Yu S, Perlmutter N, Nakao Y, Naito R, Lin C, Riekher V, DeRisi J, Ye CJ, Weiss A, Ashouri JF. Endogenous antigens shape the transcriptome and TCR repertoire in an autoimmune arthritis model. The Journal of clinical investigation 2024. PMID: 39589811


  2. Weiss A. Peeking Into the Black Box of T Cell Receptor Signaling. Annual review of immunology 2023. PMID: 37788477


  3. Tsai YL, Arias-Badia M, Kadlecek TA, Lwin YM, Srinath A, Shah NH, Wang ZE, Barber D, Kuriyan J, Fong L, Weiss A. TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments. Immunity 2023. PMID: 38091950


  4. Nguyen TTT, Lu W, Zhu WS, Ansel KM, Liang HE, Weiss A. Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells. Proceedings of the National Academy of Sciences of the United States of America 2023. PMID: 37307442


  5. Lo WL, Kuhlmann M, Rizzuto G, Ekiz HA, Kolawole EM, Revelo MP, Andargachew R, Li Z, Tsai YL, Marson A, Evavold BD, Zehn D, Weiss A. A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nature immunology 2023. PMID: 36914891


  6. Kagan JC, Rothenberg EV, Weiss A, Rudensky AY, Smale ST. Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology. Trends in immunology 2023. PMID: 36907684


  7. Lu W, Helou YA, Shrinivas K, Liou J, Au-Yeung BB, Weiss A. The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P2 replenishment in response to TCR signaling during T cell development and survival. Nature immunology 2022. PMID: 36581712


  8. Yuan-Li Tsai, Marcel Arias Badia, Theresa A Kadlecek, Neel H Shah, Lawrence Fong, Arthur Weiss. Overcoming inhibitory constraints to TCR signaling by targeting the pH-sensitive phosphatase suppressor of T-cell receptor signaling 1 (STS1). The Journal of Immunology 2022. PMID:


  9. Wen Lu, Ynes A Helou, Byron B Au-Yeung, Krishna Shrinivas, Jen Liou, Arthur Weiss. The phosphatidylinositol-transfer protein Nir3 modulates T cell development and function. The Journal of Immunology 2022. PMID:


  10. Ashouri JF, Lo WL, Nguyen TTT, Shen L, Weiss A. ZAP70, too little, too much can lead to autoimmunity. A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 2021. PMID: 34923645


  11. Huang F, Nguyen TT, Echeverria I, Ramachandran R, Cary DC, Paculova H, Sali A, Weiss A, Peterlin BM, Fujinaga K. Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb. A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 2021. PMID: 34821217


  12. Lu W, Skrzypczynska KM, Weiss A. Acute Csk inhibition hinders B cell activation by constraining the PI3 kinase pathway. A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 2021. PMID: 34675079


  13. Jeffrey Bluestone, Arthur Weiss. Frank W. Fitch, M.D. Ph.D., 1929–2021. The Journal of Immunology 2021. PMID:


  14. Nguyen TTT, Wang ZE, Shen L, Schroeder A, Eckalbar W, Weiss A. Cbl-b deficiency prevents functional but not phenotypic T cell anergy. The Journal of experimental medicine 2021. PMID: 33974042


  15. Lo WL, Weiss A. Adapting T Cell Receptor Ligand Discrimination Capability via LAT. Frontiers in immunology 2021. PMID: 33936119


  16. Shen L, Matloubian M, Kadlecek TA, Weiss A. A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self-ligands. Science signaling 2021. PMID: 33531381


  17. Byron B Au-Yeung, Arthur Weiss, Wendy Zinzow-Kramer. Basal TCR signaling drives the functional heterogeneity of naïve CD4+ T cells. The Journal of Immunology 2020. PMID:


  18. Wendy M. Zinzow-Kramer, Arthur Weiss, Byron B Au-Yeung. CD4+ T cells are more sensitive to inhibition of TCR signaling under Th17 polarizing conditions. The Journal of Immunology 2020. PMID:


  19. Ynes Helou, Byron B Au-Yeung, Arthur Weiss. The phosphatidinositol-transfer protein Nir3 is a modulator of T cell development. The Journal of Immunology 2020. PMID:


  20. Laura M. Nocka, Jean K. Chung, Aubrianna Decker, Theresa Kadlecek, Arthur Weiss, John Kuriyan, Jay T. Groves. Bruton's Tyrosine Kinase Membrane Dynamics and Signaling. Biophysical Journal 2020. PMID:


  21. Raman S. Ganti, Wan-Lin Lo, Darren McAffee, Jay T. Groves, Arthur Weiss, Arup K. Chakraborty. How the T Cell Signaling Network Processes Information to Discriminate between Self and Cognate Ligands. Biophysical Journal 2020. PMID:


  22. Courtney AH, Shvets AA, Lu W, Griffante G, Mollenauer M, Horkova V, Lo WL, Yu S, Stepanek O, Chakraborty AK, Weiss A. CD45 functions as a signaling gatekeeper in T cells. Science signaling 2019. PMID: 31641081


  23. Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A. Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination. Nature immunology 2019. PMID: 31611699


  24. Ashouri JF, Hsu LY, Yu S, Rychkov D, Chen Y, Cheng DA, Sirota M, Hansen E, Lattanza L, Zikherman J, Weiss A. Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis. Proceedings of the National Academy of Sciences of the United States of America 2019. PMID: 31455730


  25. Wang Y, Huynh W, Skokan TD, Lu W, Weiss A, Vale RD. CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic. The Journal of cell biology 2019. PMID: 30814157


  26. Nagy Z, Vögtle T, Geer MJ, Mori J, Heising S, Di Nunzio G, Gareus R, Tarakhovsky A, Weiss A, Neel BG, Desanti GE, Mazharian A, Senis YA. The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions. Blood 2018. PMID: 30429161


  27. Lo WL, Shah NH, Ahsan N, Horkova V, Stepanek O, Salomon AR, Kuriyan J, Weiss A. Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT. Nature immunology 2018. PMID: 29915297


  29. Mori J, Nagy Z, Di Nunzio G, Smith CW, Geer MJ, Al Ghaithi R, van Geffen JP, Heising S, Boothman L, Tullemans BME, Correia JN, Tee L, Kuijpers MJE, Harrison P, Heemskerk JWM, Jarvis GE, Tarakhovsky A, Weiss A, Mazharian A, Senis YA. Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148. Blood 2018. PMID: 29301754


  30. Smith GA, Taunton J, Weiss A. IL-2Rß abundance differentially tunes IL-2 signaling dynamics in CD4+ and CD8+ T cells. Science signaling 2017. PMID: 29259099


  31. Courtney AH, Lo WL, Weiss A. TCR Signaling: Mechanisms of Initiation and Propagation. Trends in biochemical sciences 2017. PMID: 29269020


  32. Courtney AH, Amacher JF, Kadlecek TA, Mollenauer MN, Au-Yeung BB, Kuriyan J, Weiss A. A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45. Molecular cell 2017. PMID: 28735895


  33. Hsu LY, Cheng DA, Chen Y, Liang HE, Weiss A. Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness. The Journal of experimental medicine 2017. PMID: 28159798


  34. Au-Yeung BB, Smith GA, Mueller JL, Heyn CS, Jaszczak RG, Weiss A, Zikherman J. IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level. Volume 198 of Issue 6. Journal of immunology (Baltimore, Md. : 1950) 2017. PMID: 28159902


  35. Visperas PR, Wilson CG, Winger JA, Yan Q, Lin K, Arkin MR, Weiss A, Kuriyan J. Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen. SLAS discovery : advancing life sciences R & D 2016. PMID: 27932698


  36. Ashouri JF, Weiss A. Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells. Journal of immunology (Baltimore, Md. : 1950) 2016. PMID: 27940659


  38. Adam H. Courtney, Theresa A. Kadlecek, Byron Au-Yeung, Arthur Weiss. Abstract A074: A Zap70-dependent negative feedback loop governs Lck activation by CD45. Other Topics 2016. PMID:


  39. Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J. An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor. eLife 2016. PMID: 27700984


  41. Esensten JH, Helou YA, Chopra G, Weiss A, Bluestone JA. CD28 Costimulation: From Mechanism to Therapy. Immunity 2016. PMID: 27192564


  42. Smith GA, Uchida K, Weiss A, Taunton J. Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling. Nature chemical biology 2016. PMID: 27018889


  43. Chan AY, Punwani D, Kadlecek TA, Cowan MJ, Olson JL, Mathes EF, Sunderam U, Fu SM, Srinivasan R, Kuriyan J, Brenner SE, Weiss A, Puck JM. A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70. The Journal of experimental medicine 2016. PMID: 26783323


  44. Adam H. Courtney, Hanna E. Sjolin-Goodfellow, Qinqin Ji, Theresa A. Kadlecek, Arthur R. Salomon, Arthur Weiss. Abstract B042: Regulation of Lck activity by a cryptic phosphosite. Immune Regulation of T Cell Responses/ Evolving Concepts in Cancer Immunology 2016. PMID:


  45. Zhengshan Chen, Huimin Geng, Clifford A. Lowell, Arthur Weiss, Stephen P. Hunger, Ari Melnick, Markus Muschen. Targeted Activation of B Cell Autoimmunity Checkpoints in Acute Lymphoblastic Leukemia. Blood 2015. PMID:


  46. Coughlin S, Noviski M, Mueller JL, Chuwonpad A, Raschke WC, Weiss A, Zikherman J. An extracatalytic function of CD45 in B cells is mediated by CD22. Volume 112 of Issue 47. Proceedings of the National Academy of Sciences of the United States of America 2015. PMID: 26561584


  47. Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. eLife 2015. PMID: 26517880


  48. Manz BN, Tan YX, Courtney AH, Rutaganira F, Palmer E, Shokat KM, Weiss A. Small molecule inhibition of Csk alters affinity recognition by T cells. eLife 2015. PMID: 26302204


  49. Zhengshan Chen, Seyedmehdi Shojaee, Maike Buchner, Huimin Geng, Jae Woong Lee, Lars Klemm, Eugene Park, Ying Xim Tan, Anne Satterthwaite, Elisabeth Paietta, Stephen P. Hunger, Mignon L. Loh, Jae U. Jung, John E. Coligan, Silvia Bolland, Tak W. Mak, Andre Limnander, Hassan Jumaa, Michael Reth, Arthur Weiss, Clifford A. Lowell, Markus Müschen. Abstract 2075: Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia. Molecular and cellular biology 2015. PMID:


  50. Goodfellow HS, Frushicheva MP, Ji Q, Cheng DA, Kadlecek TA, Cantor AJ, Kuriyan J, Chakraborty AK, Salomon A, Weiss A. The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway. Science signaling 2015. PMID: 25990959


  52. Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature 2015. PMID: 25799995


  53. Tian R, Wang H, Gish GD, Petsalaki E, Pasculescu A, Shi Y, Mollenauer M, Bagshaw RD, Yosef N, Hunter T, Gingras AC, Weiss A, Pawson T. Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. Proceedings of the National Academy of Sciences of the United States of America 2015. PMID: 25829543


  54. Mills RE, Lam VC, Tan A, Cresalia N, Oksenberg N, Zikherman J, Anderson M, Weiss A, Hermiston ML. Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production. Volume 194 of Issue 8. Journal of immunology (Baltimore, Md. : 1950) 2015. PMID: 25769918


  55. Byron B Au-Yeung, Heather J Melichar, Jenny O Ross, Debra A Cheng, Julie Zikherman, Kevan M Shokat, Ellen A Robey, Arthur Weiss. Erratum: Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. Nature immunology 2015. PMID:


  56. Punwani D, Wang H, Chan AY, Cowan MJ, Mallott J, Sunderam U, Mollenauer M, Srinivasan R, Brenner SE, Mulder A, Claas FH, Weiss A, Puck JM. Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation. Journal of clinical immunology 2015. PMID: 25627829


  57. Visperas PR, Winger JA, Horton TM, Shah NH, Aum DJ, Tao A, Barros T, Yan Q, Wilson CG, Arkin MR, Weiss A, Kuriyan J. Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding. The Biochemical journal 2015. PMID: 25287889


  58. Chakraborty AK, Weiss A. Insights into the initiation of TCR signaling. Nature immunology 2014. PMID: 25137454


  59. Au-Yeung BB, Zikherman J, Mueller JL, Ashouri JF, Matloubian M, Cheng DA, Chen Y, Shokat KM, Weiss A. A sharp T-cell antigen receptor signaling threshold for T-cell proliferation. Volume 111 of Issue 35. Proceedings of the National Academy of Sciences of the United States of America 2014. PMID: 25136127


  60. Schim van der Loeff I, Hsu LY, Saini M, Weiss A, Seddon B. Zap70 is essential for long-term survival of naive CD8 T cells. Journal of immunology (Baltimore, Md. : 1950) 2014. PMID: 25092893


  61. Ross JO, Melichar HJ, Au-Yeung BB, Herzmark P, Weiss A, Robey EA. Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns. Proceedings of the National Academy of Sciences of the United States of America 2014. PMID: 24927565


  62. Au-Yeung BB, Melichar HJ, Ross JO, Cheng DA, Zikherman J, Shokat KM, Robey EA, Weiss A. Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. Volume 15 of Issue 7. 2014. PMID: 24908390


  63. Phee H, Au-Yeung BB, Pryshchep O, O'Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A. Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation. eLife 2014. PMID: 24843022


  64. Wang H, Flach H, Onizawa M, Wei L, McManus MT, Weiss A. Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210. Nature immunology 2014. PMID: 24608041


  65. Jenkins MR, Stinchcombe JC, Au-Yeung BB, Asano Y, Ritter AT, Weiss A, Griffiths GM. Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL. eLife 2014. PMID: 24596147


  66. Limnander A, Zikherman J, Lau T, Leitges M, Weiss A, Roose JP. Protein kinase Cd promotes transitional B cell-negative selection and limits proximal B cell receptor signaling to enforce tolerance. Volume 34 of Issue 8. 2014. PMID: 24515435


  67. Maria P. Frushicheva, Arthur Weiss, Arup K. Chakraborty. Investigation of Novel Zap-70 Functionality in T Cell Signaling Pathways using Computational Modeling. Biophysical Journal 2014. PMID:


  68. Tan YX, Manz BN, Freedman TS, Zhang C, Shokat KM, Weiss A. Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling. Nature immunology 2013. PMID: 24317039


  69. Weiss A. Tony Pawson: Modular protein domains and the links to intracellular signaling. Proceedings of the National Academy of Sciences of the United States of America 2013. PMID: 24135003


  71. Gardner JM, Metzger TC, McMahon EJ, Au-Yeung BB, Krawisz AK, Lu W, Price JD, Johannes KP, Satpathy AT, Murphy KM, Tarbell KV, Weiss A, Anderson MS. Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4? T cells. Immunity 2013. PMID: 23993652


  72. Xie M, Hong C, Zhang B, Lowdon RF, Xing X, Li D, Zhou X, Lee HJ, Maire CL, Ligon KL, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, O'Geen H, Farnham PJ, Madden PA, Mungall AJ, Tam A, Kamoh B, Cho S, Moore R, Hirst M, Marra MA, Costello JF, Wang T. DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nature genetics 2013. PMID: 23708189


  73. Katsumoto TR, Kudo M, Chen C, Sundaram A, Callahan EC, Zhu JW, Lin J, Rosen CE, Manz BN, Lee JW, Matthay MA, Huang X, Sheppard D, Weiss A. The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases. The Journal of clinical investigation 2013. PMID: 23543053


  74. Yan Q, Barros T, Visperas PR, Deindl S, Kadlecek TA, Weiss A, Kuriyan J. Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker. Molecular and cellular biology 2013. PMID: 23530057


  75. Zikherman J, Parameswaran R, Hermiston M, Weiss A. The structural wedge domain of the receptor-like tyrosine phosphatase CD45 enforces B cell tolerance by regulating substrate specificity. Volume 190 of Issue 6. Journal of immunology (Baltimore, Md. : 1950) 2013. PMID: 23396948


  76. Mukherjee S, Zhu J, Zikherman J, Parameswaran R, Kadlecek TA, Wang Q, Au-Yeung B, Ploegh H, Kuriyan J, Das J, Weiss A. Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases. Volume 6 of Issue 256. 2013. PMID: 23281368


  77. Arthur Weiss, Jayajit Das, Annalisa M. VanHook. Science Signaling Podcast: 1 January 2013. A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 2013. PMID:


  78. Charles JF, Hsu LY, Niemi EC, Weiss A, Aliprantis AO, Nakamura MC. Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. Volume 122 of Issue 12. The Journal of clinical investigation 2012. PMID: 23114597


  79. Zikherman J, Parameswaran R, Weiss A. Endogenous antigen tunes the responsiveness of naive B cells but not T cells. Volume 489 of Issue 7414. 2012. PMID: 22902503


  80. Wei P, Wong WW, Park JS, Corcoran EE, Peisajovich SG, Onuffer JJ, Weiss A, Lim WA. Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature 2012. PMID: 22820255


  81. Park CY, Jeker LT, Carver-Moore K, Oh A, Liu HJ, Cameron R, Richards H, Li Z, Adler D, Yoshinaga Y, Martinez M, Nefadov M, Abbas AK, Weiss A, Lanier LL, de Jong PJ, Bluestone JA, Srivastava D, McManus MT. A resource for the conditional ablation of microRNAs in the mouse. Cell reports 2012. PMID: 22570807


  82. Abel SM, Roose JP, Groves JT, Weiss A, Chakraborty AK. The membrane environment can promote or suppress bistability in cell signaling networks. The journal of physical chemistry. B 2012. PMID: 22332778


  83. Baldari CT, Acuto O, Batista F, Koretzky G, Weiss A. Lymphocyte signaling: a Tuscan affair. Nature immunology 2011. PMID: 22179269


  84. Zikherman J, Doan K, Parameswaran R, Raschke W, Weiss A. Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival. Volume 109 of Issue 1. Proceedings of the National Academy of Sciences of the United States of America 2011. PMID: 22135465


  85. Zikherman J, Weiss A. Unraveling the functional implications of GWAS: how T cell protein tyrosine phosphatase drives autoimmune disease. Volume 121 of Issue 12. The Journal of clinical investigation 2011. PMID: 22080861


  87. Markegard E, Trager E, Yang CW, Zhang W, Weiss A, Roose JP. Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRa gene expression. PloS one 2011. PMID: 21966541


  88. Draber P, Vonkova I, Stepanek O, Hrdinka M, Kucova M, Skopcova T, Otahal P, Angelisova P, Horejsi V, Yeung M, Weiss A, Brdicka T. SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling. Molecular and cellular biology 2011. PMID: 21930792


  89. Schoenborn JR, Tan YX, Zhang C, Shokat KM, Weiss A. Feedback circuits monitor and adjust basal Lck-dependent events in T cell receptor signaling. Science signaling 2011. PMID: 21917715


  90. Limnander A, Weiss A. Ca-dependent Ras/Erk signaling mediates negative selection of autoreactive B cells. Small GTPases 2011. PMID: 22292132


  91. Stepanek O, Kalina T, Draber P, Skopcova T, Svojgr K, Angelisova P, Horejsi V, Weiss A, Brdicka T. Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148. The Journal of biological chemistry 2011. PMID: 21543337


  92. Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan AS, Magee AS, Danielson ME, Weiss A, Vasilakos JP, Underhill DM. Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature 2011. PMID: 21525931


  93. Byron Au-Yeung, Debra Cheng, Chao Zhang, Kevan Shokat, Arthur Weiss. A genetically selective inhibitor reveals ZAP-70 kinase-dependent checkpoints in T cell development (64.15). The Journal of Immunology 2011. PMID:


  94. Ying Xim Tan, Jamie Schoenborn, Chao Zhang, Kevan Shokat, Arthur Weiss. A novel analog-sensitive allele of Csk reveals its kinase-independent role in the regulation of T cell receptor signaling (109.35). The Journal of Immunology 2011. PMID:


  95. Robyn Mills, Viola Lam, Diana Tobler, Nir Oksenberg, Nicole Cresalia, Mark Anderson, Jian-Hua Mao, Arthur Weiss, Michelle Hermiston. Impact of TLR9 on hyper-responsive ITAM signaling in a mouse model of SLE (47.24). The Journal of Immunology 2011. PMID:


  96. Hyewon Phee, Ivan Dzhagalov, Marianne Mollenauer, Yana Wang, Darrell Irvine, Ellen Robey, Arthur Weiss. Regulation of thymocyte positive selection and motility by GIT2 (113.9). The Journal of Immunology 2011. PMID:


  97. Andre Limnander, Philippe Depeille, Tanya Freedman, Jen Liou, Michael Leitges, Tomohiro Kurosaki, Jeroen Roose, Arthur Weiss. Stim1, PKCd and RasGRP proteins set a threshold for pro-apoptotic Erk signaling during B cell development (109.6). The Journal of Immunology 2011. PMID:


  98. Julie Zikherman, Kristin Doan, William Raschke, Arthur Weiss. Titration of CD45 expression regulates sequential tolerance checkpoints during B cell development (45.2). The Journal of Immunology 2011. PMID:


  99. Limnander A, Depeille P, Freedman TS, Liou J, Leitges M, Kurosaki T, Roose JP, Weiss A. STIM1, PKC-d and RasGRP set a threshold for proapoptotic Erk signaling during B cell development. Nature immunology 2011. PMID: 21441934


  100. Hesslein DG, Palacios EH, Sun JC, Beilke JN, Watson SR, Weiss A, Lanier LL. Differential requirements for CD45 in NK-cell function reveal distinct roles for Syk-family kinases. Blood 2011. PMID: 21245479


  101. Liontos LM, Dissanayake D, Ohashi PS, Weiss A, Dragone LL, McGlade CJ. The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation. Journal of immunology (Baltimore, Md. : 1950) 2011. PMID: 21220694


  102. Au-Yeung BB, Levin SE, Zhang C, Hsu LY, Cheng DA, Killeen N, Shokat KM, Weiss A. A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity. Nature immunology 2010. PMID: 21037577


  103. Beinke S, Phee H, Clingan JM, Schlessinger J, Matloubian M, Weiss A. Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate. Proceedings of the National Academy of Sciences of the United States of America 2010. PMID: 20805505


  104. Phee H, Dzhagalov I, Mollenauer M, Wang Y, Irvine DJ, Robey E, Weiss A. Regulation of thymocyte positive selection and motility by GIT2. Nature immunology 2010. PMID: 20431621


  105. Wang H, Kadlecek TA, Au-Yeung BB, Goodfellow HE, Hsu LY, Freedman TS, Weiss A. ZAP-70: an essential kinase in T-cell signaling. Cold Spring Harbor perspectives in biology 2010. PMID: 20452964


  106. Zikherman J, Jenne C, Watson S, Doan K, Raschke W, Goodnow CC, Weiss A. CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development. Volume 32 of Issue 3. 2010. PMID: 20346773


  108. Michelle L. Hermiston, Vikas Gupta, Arthur Weiss. Chapter 95 CD45. Handbook of Cell Signaling 2010. PMID:


  109. Deindl S, Kadlecek TA, Cao X, Kuriyan J, Weiss A. Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response. Proceedings of the National Academy of Sciences of the United States of America 2009. PMID: 19920178


  110. Dragone LL, Shaw LA, Myers MD, Weiss A. SLAP, a regulator of immunoreceptor ubiquitination, signaling, and trafficking. Immunological reviews 2009. PMID: 19909366


  111. Hsu LY, Tan YX, Xiao Z, Malissen M, Weiss A. A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity. The Journal of experimental medicine 2009. PMID: 19841086


  112. Weiss A. TCR signal transduction: opening the black box. Journal of immunology (Baltimore, Md. : 1950) 2009. PMID: 19801506


  113. Chakraborty AK, Das J, Zikherman J, Yang M, Govern CC, Ho M, Weiss A, Roose J. Molecular origin and functional consequences of digital signaling and hysteresis during Ras activation in lymphocytes. Volume 2 of Issue 66. 2009. PMID: 19366993


  114. Jamie R Schoenborn, Chao Zhang, Kevan M Shokat, Arthur Weiss. A chemical-genetic approach to inhibit Csk activates T cells independently of the T cell receptor (35.4). The Journal of Immunology 2009. PMID:


  116. Julie Zikherman, Susan Watson, Craig Jenne, William C. Raschke, Christopher Goodnow, Arthur Weiss. An allelic series of CD45 dosages uncouples basal and inducible TCR signaling during thymic development (84.13). The Journal of Immunology 2009. PMID:


  117. Byron B Au-Yeung, Susan E Levin, Chao Zhang, Kevan Shokat, Arthur Weiss. Identifying ZAP-70 kinase-dependent and -independent functions in T cells using a chemical genetic approach (35.5). The Journal of Immunology 2009. PMID:


  118. Zikherman J, Hermiston M, Steiner D, Hasegawa K, Chan A, Weiss A. PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background. Volume 182 of Issue 7. Journal of immunology (Baltimore, Md. : 1950) 2009. PMID: 19299707


  119. Hyewon Phee, Marianne N. Mollenauer, Arthur Weiss. Role of GIT2 in T cell migration and development (95.8). The Journal of Immunology 2009. PMID:


  120. Au-Yeung BB, Deindl S, Hsu LY, Palacios EH, Levin SE, Kuriyan J, Weiss A. The structure, regulation, and function of ZAP-70. Immunological reviews 2009. PMID: 19290920


  121. Senis YA, Tomlinson MG, Ellison S, Mazharian A, Lim J, Zhao Y, Kornerup KN, Auger JM, Thomas SG, Dhanjal T, Kalia N, Zhu JW, Weiss A, Watson SP. The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis. Blood 2009. PMID: 19246339


  122. Zikherman J, Weiss A. Antigen receptor signaling in the rheumatic diseases. Volume 11 of Issue 1. 2009. PMID: 19232064


  123. Das J, Ho M, Zikherman J, Govern C, Yang M, Weiss A, Chakraborty AK, Roose JP. Digital signaling and hysteresis characterize ras activation in lymphoid cells. Volume 136 of Issue 2. 2009. PMID: 19167334


  124. Hermiston ML, Zikherman J, Tan AL, Lam VC, Cresalia NM, Oksenberg N, Goren N, Brassat D, Oksenberg JR, Weiss A. Differential impact of the CD45 juxtamembrane wedge on central and peripheral T cell receptor responses. Volume 106 of Issue 2. Proceedings of the National Academy of Sciences of the United States of America 2009. PMID: 19129486


  125. Zikherman J, Weiss A. Alternative splicing of CD45: the tip of the iceberg. Volume 29 of Issue 6. 2008. PMID: 19100695


  126. Prasad A, Zikherman J, Das J, Roose JP, Weiss A, Chakraborty AK. Origin of the sharp boundary that discriminates positive and negative selection of thymocytes. Volume 106 of Issue 2. Proceedings of the National Academy of Sciences of the United States of America 2008. PMID: 19098101


  127. Louvet C, Szot GL, Lang J, Lee MR, Martinier N, Bollag G, Zhu S, Weiss A, Bluestone JA. Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice. Proceedings of the National Academy of Sciences of the United States of America 2008. PMID: 19015530


  128. Gupta VA, Hermiston ML, Cassafer G, Daikh DI, Weiss A. B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency. The Journal of experimental medicine 2008. PMID: 19001138


  129. Mingueneau M, Sansoni A, Grégoire C, Roncagalli R, Aguado E, Weiss A, Malissen M, Malissen B. The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes. Nature immunology 2008. PMID: 18408722


  130. Levin SE, Zhang C, Kadlecek TA, Shokat KM, Weiss A. Inhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling. The Journal of biological chemistry 2008. PMID: 18378687


  131. Zhu JW, Brdicka T, Katsumoto TR, Lin J, Weiss A. Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling. Immunity 2008. PMID: 18249142


  132. Siggs OM, Miosge LA, Yates AL, Kucharska EM, Sheahan D, Brdicka T, Weiss A, Liston A, Goodnow CC. Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions. Immunity 2007. PMID: 18093540


  133. Palacios EH, Weiss A. Distinct roles for Syk and ZAP-70 during early thymocyte development. The Journal of experimental medicine 2007. PMID: 17606633


  134. Schmalzigaug R, Phee H, Davidson CE, Weiss A, Premont RT. Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007. PMID: 17565117


  135. Deindl S, Kadlecek TA, Brdicka T, Cao X, Weiss A, Kuriyan J. Structural basis for the inhibition of tyrosine kinase activity of ZAP-70. Cell 2007. PMID: 17512407


  136. Chung SC, Limnander A, Kurosaki T, Weiss A, Korenbrot JI. Coupling Ca2+ store release to Icrac channel activation in B lymphocytes requires the activity of Lyn and Syk kinases. The Journal of cell biology 2007. PMID: 17452533


  137. Hyewon Phee, Arthur Weiss. Generation and characterization of GIT1 and GIT2 deficient mice (87.18). The Journal of Immunology 2007. PMID:


  138. Roose JP, Mollenauer M, Ho M, Kurosaki T, Weiss A. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes. Molecular and cellular biology 2007. PMID: 17283063


  139. Balachandran P, Dragone L, Garrity-Ryan L, Lemus A, Weiss A, Engel J. The ubiquitin ligase Cbl-b limits Pseudomonas aeruginosa exotoxin T-mediated virulence. The Journal of clinical investigation 2007. PMID: 17235393


  140. Dragone LL, Myers MD, White C, Gadwal S, Sosinowski T, Gu H, Weiss A. Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner. Proceedings of the National Academy of Sciences of the United States of America 2006. PMID: 17110436


  141. Michelle L. Hermiston, Nicole M. Cresalia, Viola Lam, Allison L. Tan, Arthur Weiss. The Phenotypic Consequences of an Activating Mutation in the Juxtamembrane Wedge of CD45 Is Sensitive to Genetic Modifiers. Blood 2006. PMID:


  142. Liguang Chen, Lang Huynh, Arthur Weiss, Thomas J. Kipps. ZAP-70 Enhances IgM Signaling in Chronic Lymphocytic Leukemia Cells Independent of Its Tyrosine Kinase Activity. Blood 2006. PMID:


  143. Nirula A, Ho M, Phee H, Roose J, Weiss A. Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4. The Journal of experimental medicine 2006. PMID: 16785309


  144. Hesslein DG, Takaki R, Hermiston ML, Weiss A, Lanier LL. Dysregulation of signaling pathways in CD45-deficient NK cells leads to differentially regulated cytotoxicity and cytokine production. Proceedings of the National Academy of Sciences of the United States of America 2006. PMID: 16627620


  145. Susan E Levin, Chao Zhang, Kevan Shokat, Arthur Weiss. Small molecule inhibition of ZAP-70 kinase activity. The FASEB Journal 2006. PMID:


  146. Dragone LL, Myers MD, White C, Sosinowski T, Weiss A. SRC-like adaptor protein regulates B cell development and function. Journal of immunology (Baltimore, Md. : 1950) 2006. PMID: 16365426


  147. Myers MD, Sosinowski T, Dragone LL, White C, Band H, Gu H, Weiss A. Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex. Nature immunology 2005. PMID: 16327786


  148. Hermiston ML, Tan AL, Gupta VA, Majeti R, Weiss A. The juxtamembrane wedge negatively regulates CD45 function in B cells. Immunity 2005. PMID: 16356861


  149. Weiss A. Discovering the TCR beta-chain by subtraction. Journal of immunology (Baltimore, Md. : 1950) 2005. PMID: 16116159


  150. Myers MD, Dragone LL, Weiss A. Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation. The Journal of cell biology 2005. PMID: 16027224


  151. Roose JP, Mollenauer M, Gupta VA, Stone J, Weiss A. A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. Molecular and cellular biology 2005. PMID: 15899849


  152. Brdicka T, Kadlecek TA, Roose JP, Pastuszak AW, Weiss A. Intramolecular regulatory switch in ZAP-70: analogy with receptor tyrosine kinases. Molecular and cellular biology 2005. PMID: 15923611


  154. Levin SE, Weiss A. Twisting tails exposed: the evidence for TCR conformational change. The Journal of experimental medicine 2005. PMID: 15728230


  156. Tomlinson MG, Heath VL, Turck CW, Watson SP, Weiss A. SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase. The Journal of biological chemistry 2004. PMID: 15492005


  157. Lin J, Zhu JW, Baker JE, Weiss A. Regulated expression of the receptor-like tyrosine phosphatase CD148 on hemopoietic cells. Journal of immunology (Baltimore, Md. : 1950) 2004. PMID: 15294945


  158. Arthur Weiss, John C Cambier. Lymphocyte activation. Current opinion in immunology 2004. PMID:


  159. Kane LP, Mollenauer MN, Weiss A. A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse. Journal of immunology (Baltimore, Md. : 1950) 2004. PMID: 15100285


  160. Crotzer VL, Mabardy AS, Weiss A, Brodsky FM. T cell receptor engagement leads to phosphorylation of clathrin heavy chain during receptor internalization. The Journal of experimental medicine 2004. PMID: 15067034


  161. Abraham RT, Weiss A. Jurkat T cells and development of the T-cell receptor signalling paradigm. Nature reviews. Immunology 2004. PMID: 15057788


  162. Andres PG, Howland KC, Nirula A, Kane LP, Barron L, Dresnek D, Sadra A, Imboden J, Weiss A, Abbas AK. Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation. Nature immunology 2004. PMID: 15004555


  163. Tomlinson MG, Kane LP, Su J, Kadlecek TA, Mollenauer MN, Weiss A. Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec. Molecular and cellular biology 2004. PMID: 14993283


  164. Roose JP, Diehn M, Tomlinson MG, Lin J, Alizadeh AA, Botstein D, Brown PO, Weiss A. T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. PLoS biology 2003. PMID: 14624253


  166. Kuhné MR, Lin J, Yablonski D, Mollenauer MN, Ehrlich LI, Huppa J, Davis MM, Weiss A. Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization. Journal of immunology (Baltimore, Md. : 1950) 2003. PMID: 12847255


  167. Kane LP, Weiss A. The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3. Immunological reviews 2003. PMID: 12670391


  168. Hartgroves LC, Lin J, Langen H, Zech T, Weiss A, Harder T. Synergistic assembly of linker for activation of T cells signaling protein complexes in T cell plasma membrane domains. The Journal of biological chemistry 2003. PMID: 12646565


  169. Zheng Xu, Michelle L. Hermiston, Arthur Weiss. Chapter 114 CD45. Handbook of Cell Signaling 2003. PMID:


  170. Ehrlich LI, Ebert PJ, Krummel MF, Weiss A, Davis MM. Dynamics of p56lck translocation to the T cell immunological synapse following agonist and antagonist stimulation. Immunity 2002. PMID: 12479826


  171. Kane LP, Mollenauer MN, Xu Z, Turck CW, Weiss A. Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription. Molecular and cellular biology 2002. PMID: 12138205


  172. Kane LP, Lin J, Weiss A. It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation. Trends in immunology 2002. PMID: 12133805


  174. Xu Z, Stokoe D, Kane LP, Weiss A. The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2002. PMID: 12133897


  175. Hermiston ML, Xu Z, Majeti R, Weiss A. Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases. The Journal of clinical investigation 2002. PMID: 11781344


  176. Hermiston ML, Xu Z, Weiss A. CD45: a critical regulator of signaling thresholds in immune cells. Annual review of immunology 2001. PMID: 12414720


  177. Barcellos LF, Caillier S, Dragone L, Elder M, Vittinghoff E, Bucher P, Lincoln RR, Pericak-Vance M, Haines JL, Weiss A, Hauser SL, Oksenberg JR. PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nature genetics 2001. PMID: 11528386


  179. Sauer K, Liou J, Singh SB, Yablonski D, Weiss A, Perlmutter RM. Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes. The Journal of biological chemistry 2001. PMID: 11487585


  180. Majeti R, Weiss A. Regulatory mechanisms for receptor protein tyrosine phosphatases. Chemical reviews 2001. PMID: 11749382


  183. Lin J, Weiss A. Identification of the minimal tyrosine residues required for linker for activation of T cell function. The Journal of biological chemistry 2001. PMID: 11395491


  184. Lynch KW, Weiss A. A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer. The Journal of biological chemistry 2001. PMID: 11306584


  186. Ku GM, Yablonski D, Manser E, Lim L, Weiss A. A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT. The EMBO journal 2001. PMID: 11157752


  187. Kratchmarova I, Sosinowski T, Weiss A, Witter K, Vincenz C, Pandey A. Characterization of promoter region and genomic structure of the murine and human genes encoding Src like adapter protein. Gene 2001. PMID: 11179692


  188. Kane LP, Andres PG, Howland KC, Abbas AK, Weiss A. Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines. Nature immunology 2001. PMID: 11135576


  189. Elder ME, Skoda-Smith S, Kadlecek TA, Wang F, Wu J, Weiss A. Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70. Journal of immunology (Baltimore, Md. : 1950) 2001. PMID: 11123350


  191. Lin J, Weiss A. T cell receptor signalling. Journal of cell science 2001. PMID: 11148124


  192. Majeti R, Xu Z, Parslow TG, Olson JL, Daikh DI, Killeen N, Weiss A. An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity. Cell 2000. PMID: 11163182


  193. Tomlinson MG, Lin J, Weiss A. Lymphocytes with a complex: adapter proteins in antigen receptor signaling. Immunology today 2000. PMID: 11094263


  194. Kane LP, Lin J, Weiss A. Signal transduction by the TCR for antigen. Current opinion in immunology 2000. PMID: 10781399


  195. Liou J, Kiefer F, Dang A, Hashimoto A, Cobb MH, Kurosaki T, Weiss A. HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1. Immunity 2000. PMID: 10795738


  196. Sosinowski T, Pandey A, Dixit VM, Weiss A. Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling. The Journal of experimental medicine 2000. PMID: 10662792


  197. Kuhne MR, Ku G, Weiss A. A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation. The Journal of biological chemistry 2000. PMID: 10636924


  198. Witherden D, van Oers N, Waltzinger C, Weiss A, Benoist C, Mathis D. Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules. The Journal of experimental medicine 2000. PMID: 10637279


  200. Lin J, Weiss A, Finco TS. Localization of LAT in glycolipid-enriched microdomains is required for T cell activation. The Journal of biological chemistry 1999. PMID: 10506128


  201. Chu DH, van Oers NS, Malissen M, Harris J, Elder M, Weiss A. Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression. Journal of immunology (Baltimore, Md. : 1950) 1999. PMID: 10453000


  202. Lagunoff M, Majeti R, Weiss A, Ganem D. Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus. Proceedings of the National Academy of Sciences of the United States of America 1999. PMID: 10318948


  203. Zhao Q, Williams BL, Abraham RT, Weiss A. Interdomain B in ZAP-70 regulates but is not required for ZAP-70 signaling function in lymphocytes. Molecular and cellular biology 1999. PMID: 9858619


  204. Finco TS, Yablonski D, Lin J, Weiss A. The adapter proteins LAT and SLP-76 are required for T-cell activation. Cold Spring Harbor symposia on quantitative biology 1999. PMID: 11232295


  205. Shapiro VS, Mollenauer MN, Weiss A. Nuclear factor of activated T cells and AP-1 are insufficient for IL-2 promoter activation: requirement for CD28 up-regulation of RE/AP. Journal of immunology (Baltimore, Md. : 1950) 1998. PMID: 9862666


  206. Kadlecek TA, van Oers NS, Lefrancois L, Olson S, Finlay D, Chu DH, Connolly K, Killeen N, Weiss A. Differential requirements for ZAP-70 in TCR signaling and T cell development. Journal of immunology (Baltimore, Md. : 1950) 1998. PMID: 9794398


  207. Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A. LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity 1998. PMID: 9846483


  208. Yablonski D, Kane LP, Qian D, Weiss A. A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK. The EMBO journal 1998. PMID: 9755165


  209. Weiss A, Schlessinger J. Switching signals on or off by receptor dimerization. Cell 1998. PMID: 9708728


  210. Yablonski D, Kuhne MR, Kadlecek T, Weiss A. Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. Science (New York, N.Y.) 1998. PMID: 9665884


  211. AnthonyL DeFranco, Arthur Weiss. Lymphocyte activation and effector functions Turning lymphocytes on and off. Current opinion in immunology 1998. PMID:


  213. van Oers NS, Love PE, Shores EW, Weiss A. Regulation of TCR signal transduction in murine thymocytes by multiple TCR zeta-chain signaling motifs. Journal of immunology (Baltimore, Md. : 1950) 1998. PMID: 9551968


  214. Liao XC, Littman DR, Weiss A. Itk and Fyn make independent contributions to T cell activation. The Journal of experimental medicine 1997. PMID: 9396778


  215. Liao XC, Fournier S, Killeen N, Weiss A, Allison JP, Littman DR. Itk negatively regulates induction of T cell proliferation by CD28 costimulation. The Journal of experimental medicine 1997. PMID: 9221751


  217. Huby RD, Iwashima M, Weiss A, Ley SC. ZAP-70 protein tyrosine kinase is constitutively targeted to the T cell cortex independently of its SH2 domains. The Journal of cell biology 1997. PMID: 9199177


  218. Wu J, Zhao Q, Kurosaki T, Weiss A. The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction. The Journal of experimental medicine 1997. PMID: 9151714


  219. Qian D, Lev S, van Oers NS, Dikic I, Schlessinger J, Weiss A. Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. The Journal of experimental medicine 1997. PMID: 9104812


  220. Qian D, Weiss A. T cell antigen receptor signal transduction. Current opinion in cell biology 1997. PMID: 9069257


  221. Chu DH, Spits H, Peyron JF, Rowley RB, Bolen JB, Weiss A. The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. The EMBO journal 1996. PMID: 8947048


  222. Taylor N, Bacon KB, Smith S, Jahn T, Kadlecek TA, Uribe L, Kohn DB, Gelfand EW, Weiss A, Weinberg K. Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene. The Journal of experimental medicine 1996. PMID: 8920891


  223. van Oers NS, Lowin-Kropf B, Finlay D, Connolly K, Weiss A. alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases. Immunity 1996. PMID: 8934570


  224. Shapiro VS, Mollenauer MN, Greene WC, Weiss A. c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1. The Journal of experimental medicine 1996. PMID: 8920856


  226. Wu J, Motto DG, Koretzky GA, Weiss A. Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity 1996. PMID: 8673706


  227. Straus DB, Chan AC, Patai B, Weiss A. SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction. The Journal of biological chemistry 1996. PMID: 8626636


  228. van Oers NS, Killeen N, Weiss A. Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes. The Journal of experimental medicine 1996. PMID: 8642247


  229. Qian D, Mollenauer MN, Weiss A. Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling. The Journal of experimental medicine 1996. PMID: 8627172


  230. Crooks ME, Littman DR, Carter RH, Fearon DT, Weiss A, Stein PH. CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation. Molecular and cellular biology 1995. PMID: 8524248


  231. Gelfand EW, Weinberg K, Mazer BD, Kadlecek TA, Weiss A. Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes. The Journal of experimental medicine 1995. PMID: 7561679


  232. Weiss A, Kadlecek T, Iwashima M, Chan A, Van Oers N. Molecular and genetic insights into T-cell antigen receptor signaling. Annals of the New York Academy of Sciences 1995. PMID: 7486651


  233. Weiss A. Molecular and genetic insights into the role of protein tyrosine kinases in T cell receptor signaling. Clinical immunology and immunopathology 1995. PMID: 7554459


  234. Wu J, Katzav S, Weiss A. A functional T-cell receptor signaling pathway is required for p95vav activity. Molecular and cellular biology 1995. PMID: 7623828


  235. Howe LR, Weiss A. Multiple kinases mediate T-cell-receptor signaling. Trends in biochemical sciences 1995. PMID: 7701563


  236. Katzav S, Sutherland M, Packham G, Yi T, Weiss A. The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav. The Journal of biological chemistry 1994. PMID: 7798261


  238. Izquierdo M, Leevers SJ, Williams DH, Marshall CJ, Weiss A, Cantrell D. The role of protein kinase C in the regulation of extracellular signal-regulated kinase by the T cell antigen receptor. European journal of immunology 1994. PMID: 7925576


  239. Desai DM, Sap J, Silvennoinen O, Schlessinger J, Weiss A. The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation. The EMBO journal 1994. PMID: 8076596


  240. M Sieh, A Batzer, J Schlessinger, A Weiss. GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation. Molecular and cellular biology 1994. PMID:


  241. Sieh M, Batzer A, Schlessinger J, Weiss A. GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation. Molecular and cellular biology 1994. PMID: 7516467


  242. Elder ME, Lin D, Clever J, Chan AC, Hope TJ, Weiss A, Parslow TG. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science (New York, N.Y.) 1994. PMID: 8202712


  243. Chan AC, Kadlecek TA, Elder ME, Filipovich AH, Kuo WL, Iwashima M, Parslow TG, Weiss A. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science (New York, N.Y.) 1994. PMID: 8202713


  244. Chan AC, van Oers NS, Tran A, Turka L, Law CL, Ryan JC, Clark EA, Weiss A. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. Journal of immunology (Baltimore, Md. : 1950) 1994. PMID: 8176201


  248. Law CL, Sidorenko SP, Chandran KA, Draves KE, Chan AC, Weiss A, Edelhoff S, Disteche CM, Clark EA. Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex. The Journal of biological chemistry 1994. PMID: 8163536


  249. van Oers NS, Teh SJ, Irving BA, Tiong J, Weiss A, Teh HS. Production and characterization of monoclonal antibodies specific for the murine T cell receptor zeta chain. Journal of immunological methods 1994. PMID: 7512608


  250. Iwashima M, Irving BA, van Oers NS, Chan AC, Weiss A. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science (New York, N.Y.) 1994. PMID: 7509083


  251. Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Cell 1994. PMID: 8293463


  252. Weiss A, Iwashima M, Irving B, van Oers NS, Kadlecek TA, Straus D, Chan A. Molecular and genetic insights into T cell antigen receptor signal transduction. Advances in experimental medicine and biology 1994. PMID: 7887313


  254. Fraser JD, Straus D, Weiss A. Signal transduction events leading to T-cell lymphokine gene expression. Immunology today 1993. PMID: 8363726


  255. Desai DM, Sap J, Schlessinger J, Weiss A. Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase. Cell 1993. PMID: 8490965


  257. Irving BA, Chan AC, Weiss A. Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain. The Journal of experimental medicine 1993. PMID: 8459204


  259. M. Iwashima, A. C. Chan, B. Irving, D. Straus, A. Weiss. Molecular Dissection of T-Cell Antigen Receptor Signal Transduction. Progress in Immunology Vol. VIII 1993. PMID:


  260. Chan AC, Iwashima M, Turck CW, Weiss A. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell 1992. PMID: 1423621


  262. Fraser JD, Weiss A. Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28. Molecular and cellular biology 1992. PMID: 1328852


  264. Koretzky GA, Kohmetscher MA, Kadleck T, Weiss A. Restoration of T cell receptor-mediated signal transduction by transfection of CD45 cDNA into a CD45-deficient variant of the Jurkat T cell line. Journal of immunology (Baltimore, Md. : 1950) 1992. PMID: 1380033


  265. Chan AC, Irving BA, Weiss A. New insights into T-cell antigen receptor structure and signal transduction. Current opinion in immunology 1992. PMID: 1418701


  267. Margolis B, Hu P, Katzav S, Li W, Oliver JM, Ullrich A, Weiss A, Schlessinger J. Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs. Nature 1992. PMID: 1531699


  268. Weiss A, Chan AC, Iwashima M, Straus D, Irving BA. Regulation of protein tyrosine kinase activation by the T-cell antigen receptor zeta chain. Cold Spring Harbor symposia on quantitative biology 1992. PMID: 1339649


  269. Chan AC, Irving BA, Fraser JD, Weiss A. The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. Proceedings of the National Academy of Sciences of the United States of America 1991. PMID: 1717999


  270. Weiss A, Irving BA, Tan LK, Koretzky GA. Signal transduction by the T cell antigen receptor. Seminars in immunology 1991. PMID: 1839225


  271. Weiss A, Koretzky G, Schatzman RC, Kadlecek T. Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1. Proceedings of the National Academy of Sciences of the United States of America 1991. PMID: 1712101


  272. Tan L, Turner J, Weiss A. Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3. The Journal of experimental medicine 1991. PMID: 1827143


  273. Graber M, Bockenstedt LK, Weiss A. Signaling via the inositol phospholipid pathway by T cell antigen receptor is limited by receptor number. Journal of immunology (Baltimore, Md. : 1950) 1991. PMID: 1826700


  274. Koretzky GA, Picus J, Schultz T, Weiss A. Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. Proceedings of the National Academy of Sciences of the United States of America 1991. PMID: 1672451


  275. Weiss A, Desai D, Graber M, Picus J, Koretzky G. The regulation of T-cell antigen receptor signal transduction function. Transplantation proceedings 1991. PMID: 1990543


  276. Fraser JD, Irving BA, Crabtree GR, Weiss A. Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science (New York, N.Y.) 1991. PMID: 1846244


  277. Weiss A. Molecular and genetic insights into T cell antigen receptor structure and function. Annual review of genetics 1991. PMID: 1839878


  278. Desai DM, Newton ME, Kadlecek T, Weiss A. Stimulation of the phosphatidylinositol pathway can induce T-cell activation. Nature 1990. PMID: 2234059


  279. Weiss A. Structure and function of the T cell antigen receptor. The Journal of clinical investigation 1990. PMID: 2211998


  281. Krensky AM, Weiss A, Crabtree G, Davis MM, Parham P. T-lymphocyte-antigen interactions in transplant rejection. The New England journal of medicine 1990. PMID: 2405272


  283. Goldsmith MA, Desai DM, Schultz T, Weiss A. Function of a heterologous muscarinic receptor in T cell antigen receptor signal transduction mutants. The Journal of biological chemistry 1989. PMID: 2529257


  284. Koretzky GA, Wahi M, Newton ME, Weiss A. Heterogeneity of protein kinase C isoenzyme gene expression in human T cell lines. Protein kinase C-beta is not required for several T cell functions. Journal of immunology (Baltimore, Md. : 1950) 1989. PMID: 2788192


  285. Fraser JD, Goldsmith MA, Weiss A. Ligand-induced association between the T-cell antigen receptor and two glycoproteins. Proceedings of the National Academy of Sciences of the United States of America 1989. PMID: 2789381


  286. Goldsmith MA, Bockenstedt LK, Dazin P, Weiss A. Use of somatic cell mutants to study the signal transduction function of the T cell antigen receptor. Advances in experimental medicine and biology 1989. PMID: 2573246


  287. Morley BJ, Chin KN, Newton ME, Weiss A. The lysine residue in the membrane-spanning domain of the beta chain is necessary for cell surface expression of the T cell antigen receptor. The Journal of experimental medicine 1988. PMID: 2974063


  288. Goldsmith MA, Dazin PF, Weiss A. At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor. Proceedings of the National Academy of Sciences of the United States of America 1988. PMID: 3263650


  289. Bockenstedt LK, Goldsmith MA, Dustin M, Olive D, Springer TA, Weiss A. The CD2 ligand LFA-3 activates T cells but depends on the expression and function of the antigen receptor. Journal of immunology (Baltimore, Md. : 1950) 1988. PMID: 2459194


  290. Goldsmith MA, Weiss A. New clues about T-cell antigen receptor complex function. Immunology today 1988. PMID: 3076421


  291. John B. Imboden, Arthur Weiss. The Initiation of Human T Lymphocyte Activation (Part 1 of 2). A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 1988. PMID:


  292. John B. Imboden, Arthur Weiss. The Initiation of Human T Lymphocyte Activation (Part 2 of 2). A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 1988. PMID:


  293. Goldsmith MA, Weiss A. Early signal transduction by the antigen receptor without commitment to T cell activation. Science (New York, N.Y.) 1988. PMID: 3259335


  294. John B. Imboden, Arthur Weiss. CHAPTER 4 REGULATION OF INTERLEUKIN 2 PRODUCTION BY THE T CELL ANTIGEN RECEPTOR. Interleukin 1988. PMID:


  295. Goldsmith MA, Weiss A. Function of the antigen receptor in T cell activation. Advances in experimental medicine and biology 1988. PMID: 3063086


  297. Bernard Manger, John Imboden, Arthur Weiss. Role of the T3/T-Cell Antigen Receptor Complex in T-Cell Activation. The T-Cell Receptors 1988. PMID:


  298. Imboden JB, Weiss A. The initiation of human T lymphocyte activation. Progress in allergy 1988. PMID: 2845427


  299. Loh EY, Lanier LL, Turck CW, Littman DR, Davis MM, Chien YH, Weiss A. Identification and sequence of a fourth human T cell antigen receptor chain. Nature 1987. PMID: 2825032


  300. Bockenstedt LK, Goldsmith MA, Koretzky GA, Weiss A. The activation of T lymphocytes. Rheumatic diseases clinics of North America 1987. PMID: 2963355


  301. Weiss A, Dazin PF, Shields R, Fu SM, Lanier LL. Functional competency of T cell antigen receptors in human thymus. Journal of immunology (Baltimore, Md. : 1950) 1987. PMID: 3500209


  302. Phillips JH, Weiss A, Gemlo BT, Rayner AA, Lanier LL. Evidence that the T cell antigen receptor may not be involved in cytotoxicity mediated by gamma/delta and alpha/beta thymic cell lines. The Journal of experimental medicine 1987. PMID: 3500263


  304. Lanier LL, Serafini AT, Ruitenberg JJ, Cwirla S, Federspiel NA, Phillips JH, Allison JP, Weiss A. The gamma T-cell antigen receptor. Journal of clinical immunology 1987. PMID: 3320076


  305. Manger B, Weiss A, Imboden J, Laing T, Stobo JD. The role of protein kinase C in transmembrane signaling by the T cell antigen receptor complex. Effects of stimulation with soluble or immobilized CD3 antibodies. Journal of immunology (Baltimore, Md. : 1950) 1987. PMID: 3116093


  306. Goldsmith MA, Weiss A. Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor. Proceedings of the National Academy of Sciences of the United States of America 1987. PMID: 3309950


  307. Pelicci PG, Subar M, Weiss A, Dalla-Favera R, Littman DR. Molecular diversity of the human T-gamma constant region genes. Science (New York, N.Y.) 1987. PMID: 3112943


  308. Saito T, Weiss A, Gunter KC, Shevach EM, Germain RN. Cell surface T3 expression requires the presence of both alpha- and beta-chains of the T cell receptor. Journal of immunology (Baltimore, Md. : 1950) 1987. PMID: 2955045


  309. Lancki DW, Weiss A, Fitch FW. Requirements for triggering of lysis by cytolytic T lymphocyte clones. Journal of immunology (Baltimore, Md. : 1950) 1987. PMID: 2953785


  310. Weiss A, Shields R, Newton M, Manger B, Imboden J. Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene. Journal of immunology (Baltimore, Md. : 1950) 1987. PMID: 3104454


  311. Lanier LL, Federspiel NA, Ruitenberg JJ, Phillips JH, Allison JP, Littman D, Weiss A. The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer. The Journal of experimental medicine 1987. PMID: 2435832


  312. Gunter KC, Germain RN, Kroczek RA, Saito T, Yokoyama WM, Chan C, Weiss A, Shevach EM. Thy-1-mediated T-cell activation requires co-expression of CD3/Ti complex. Nature 1987. PMID: 3104795


  313. Littman DR, Newton M, Crommie D, Ang SL, Seidman JG, Gettner SN, Weiss A. Characterization of an expressed CD3-associated Ti gamma-chain reveals C gamma domain polymorphism. Nature 1987. PMID: 3102973


  315. Weiss A, Imboden JB. Cell surface molecules and early events involved in human T lymphocyte activation. Advances in immunology 1987. PMID: 2961214


  316. Saito T, Weiss A, Miller J, Norcross MA, Germain RN. Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes. Nature 1987. PMID: 3027582


  317. Weiss A, Imboden J, Hardy K, Stobo J. The role of the antigen receptor/T3 complex in T-cell activation. Advances in experimental medicine and biology 1987. PMID: 2957896


  318. Lanier LL, Weiss A. Presence of Ti (WT31) negative T lymphocytes in normal blood and thymus. Nature 1986. PMID: 3491323


  319. Lanier LL, Ruitenberg JJ, Allison JP, Weiss A. Distinct epitopes on the T cell antigen receptor of HPB-ALL tumor cells identified by monoclonal antibodies. Journal of immunology (Baltimore, Md. : 1950) 1986. PMID: 2428866


  320. Weiss A, Manger B, Imboden J. Synergy between the T3/antigen receptor complex and Tp44 in the activation of human T cells. Journal of immunology (Baltimore, Md. : 1950) 1986. PMID: 3088111


  321. Manger B, Hardy KJ, Weiss A, Stobo JD. Differential effect of cyclosporin A on activation signaling in human T cell lines. The Journal of clinical investigation 1986. PMID: 2422208


  322. Manger B, Weiss A, Hardy KJ, Stobo JD. A transferrin receptor antibody represents one signal for the induction of IL 2 production by a human T cell line. Journal of immunology (Baltimore, Md. : 1950) 1986. PMID: 3001178


  323. Weiss A, Imboden J, Hardy K, Manger B, Terhorst C, Stobo J. The role of the T3/antigen receptor complex in T-cell activation. Annual review of immunology 1986. PMID: 2939858


  324. Manger B, Weiss A, Weyand C, Goronzy J, Stobo JD. T cell activation: differences in the signals required for IL 2 production by nonactivated and activated T cells. Journal of immunology (Baltimore, Md. : 1950) 1985. PMID: 3934263


  325. Imboden JB, Weiss A, Stobo JD. Transmembrane signalling by the T3-antigen receptor complex. Immunology today 1985. PMID: 25291003


  326. Ohashi PS, Mak TW, Van den Elsen P, Yanagi Y, Yoshikai Y, Calman AF, Terhorst C, Stobo JD, Weiss A. Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer. Nature 1985. PMID: 4033759


  327. Wiskocil R, Weiss A, Imboden J, Kamin-Lewis R, Stobo J. Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes. Journal of immunology (Baltimore, Md. : 1950) 1985. PMID: 3918105


  328. Imboden JB, Weiss A, Stobo JD. The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium. Journal of immunology (Baltimore, Md. : 1950) 1985. PMID: 3871211


  329. Weiss A, Stobo JD. Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. The Journal of experimental medicine 1984. PMID: 6208306


  330. Weiss A, Imboden J, Shoback D, Stobo J. Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. Proceedings of the National Academy of Sciences of the United States of America 1984. PMID: 6234599


  332. Weiss A, Imboden J, Wiskocil R, Stobo J. The role of T3 in the activation of human T cells. Journal of clinical immunology 1984. PMID: 6203926


  335. Stuart FP, McKearn TJ, Weiss A, Fitch FW. Suppression of rat renal allograft rejection by antigen and antibody. Immunological reviews 1980. PMID: 6989746


  337. Weiss A, Stuart FP, Fitch FW. Immune reactivity of cells from long-term rat renal allograft survivors. Transplantation 1978. PMID: 151955


  338. Weiss A, Fitch FW, McKearn TJ, Stuart FP. Immunological memory is regulated in the enhanced rat renal allograft recipient. Nature 1978. PMID: 351414


  340. Weiss A, Fitch FW. Suppression of the plaque-forming cell response by macrophages present in the normal rat spleen. Journal of immunology (Baltimore, Md. : 1950) 1978. PMID: 621383


  341. Weiss A, Stuart FP, Fitch FW. Absence of immunologic memory in recipients of enhanced renal allografts. Surgical forum 1978. PMID: 162608


  342. McKearn TJ, Sarmiento M, Weiss A, Stuart FP, Fitch FW. Selective suppression of reactivity to rat histocompatibility antigens by hybridoma antibodies. Current topics in microbiology and immunology 1978. PMID: 308442


  343. Weiss A, Fitch FW. Macrophages suppress CTL generation in rat mixed leukocyte cultures. Journal of immunology (Baltimore, Md. : 1950) 1977. PMID: 142114


  344. Weiss A. Suppression of adult rat lymphoid proliferative responses by homologous neonatal serum. Journal of immunology (Baltimore, Md. : 1950) 1977. PMID: 139446


  345. Edidin M, Weiss A. Antigen cap formation in cultured fibroblasts: a reflection of membrane fluidity and of cell motility. Proceedings of the National Academy of Sciences of the United States of America 1972. PMID: 4560687