Renuka Nayak, MD, PhD

Education
2022 - Diversity, Equity, and Inclusion Champion Training, University of California
2017 - Rheumatology, UCSF
2014 - Internal Medicine, UCSF
MD, PhD, 2012 - Genomics, University of Pennsylvania
BA, 2004 - Biology, Swarthmore College
BA, 2004 - Computer Science, Swarthmore College
Publications

  1. Blank RB, Nayak RR, Scher JU. Can we modulate the gut microbiome to enhance DMARD efficacy in rheumatoid arthritis? Seminars in arthritis and rheumatism 2024. PMID: 39551674


  2. Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity. Cell reports 2024. PMID: 39500329


  3. Scher JU, Nayak R, Clemente JC. Microbiome research in autoimmune and immune-mediated inflammatory diseases: lessons, advances and unmet needs. Annals of the rheumatic diseases 2024. PMID: 39419539


  4. Nayak RR, Orellana DA. The impact of the human gut microbiome on the treatment of autoimmune disease. Immunological reviews 2024. PMID: 38864582


  5. Alexander M, Upadhyay V, Rock R, Ramirez L, Puchalska P, Orellana D, Ang QY, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity. bioRxiv : the preprint server for biology 2023. PMID: 37961209


  6. Wu KC, McCauley KE, Lynch SV, Nayak RR, King NJ, Patel S, Kim TY, Condra K, Fadrosh D, Nguyen D, Lin DL, Lynch K, Rogers SJ, Carter JT, Posselt AM, Stewart L, Schafer AL. Alteration in the gut microbiome is associated with changes in bone metabolism after laparoscopic sleeve gastrectomy. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2024. PMID: 38477719


  7. Escalante V, Nayak RR, Noecker C, Babdor J, Spitzer M, Deutschbauer AM, Turnbaugh PJ. Simvastatin induces human gut bacterial cell surface genes. Molecular microbiology 2023. PMID: 37712143


  9. Nayak RR. Fanning the flames of autoimmunity: the microbiome in rheumatic disease. A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 2021. PMID: 34962101


  10. Alexander M, Ang QY, Nayak RR, Bustion AE, Sandy M, Zhang B, Upadhyay V, Pollard KS, Lynch SV, Turnbaugh PJ. Human gut bacterial metabolism drives Th17 activation and colitis. A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 2021. PMID: 34822777


  11. Lam KN, Spanogiannopoulos P, Soto-Perez P, Alexander M, Nalley MJ, Bisanz JE, Nayak RR, Weakley AM, Yu FB, Turnbaugh PJ. Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome. A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 2021. PMID: 34731631


  12. Nayak RR. Western Diet and Psoriatic-Like Skin and Joint Diseases: A Potential Role for the Gut Microbiota. The Journal of investigative dermatology 2021. PMID: 34167722


  13. Artacho A, Isaac S, Nayak R, Flor-Duro A, Alexander M, Koo I, Manasson J, Smith PB, Rosenthal P, Homsi Y, Gulko P, Pons J, Puchades-Carrasco L, Izmirly P, Patterson A, Abramson SB, Pineda-Lucena A, Turnbaugh PJ, Ubeda C, Scher JU. The Pretreatment Gut Microbiome Is Associated With Lack of Response to Methotrexate in New-Onset Rheumatoid Arthritis. A pilot telephone-based intervention for patients with poorly-controlled diabetes mellitus. 2021. PMID: 33314800


  14. Nayak RR, Alexander M, Deshpande I, Stapleton-Gray K, Rimal B, Patterson AD, Ubeda C, Scher JU, Turnbaugh PJ. Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation. Cell host & microbe 2021. PMID: 33440172


  15. Scher JU, Nayak RR, Ubeda C, Turnbaugh PJ, Abramson SB. Pharmacomicrobiomics in inflammatory arthritis: gut microbiome as modulator of therapeutic response. Nature reviews. Rheumatology 2020. PMID: 32157196


  16. Mok A, Solomon O, Nayak RR, Coit P, Quach HL, Nititham J, Sawalha AH, Barcellos LF, Criswell LA, Chung SA. Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses. Volume 3 of Issue 1. Lupus science & medicine 2016. PMID: 28074145


  17. Nayak RR, Turnbaugh PJ. Mirror, mirror on the wall: which microbiomes will help heal them all? Volume 14. BMC medicine 2016. PMID: 27146150


  18. Nayak RR, Bernal WE, Lee JW, Kearns MJ, Cheung VG. Stress-induced changes in gene interactions in human cells. Volume 42 of Issue 3. Nucleic acids research 2013. PMID: 24170811


  19. Cheung VG, Nayak RR, Wang IX, Elwyn S, Cousins SM, Morley M, Spielman RS. Polymorphic cis- and trans-regulation of human gene expression. Volume 8 of Issue 9. PLoS biology 2010. PMID: 20856902


  20. Dombroski BA, Nayak RR, Ewens KG, Ankener W, Cheung VG, Spielman RS. Gene expression and genetic variation in response to endoplasmic reticulum stress in human cells. Volume 86 of Issue 5. American journal of human genetics 2010. PMID: 20398888


  21. Nayak RR, Kearns M, Spielman RS, Cheung VG. Coexpression network based on natural variation in human gene expression reveals gene interactions and functions. Volume 19 of Issue 11. Genome research 2009. PMID: 19797678