Renuka Nayak, MD, PhD

Assistant Professor

Dr. Renuka Nayak, MD, PhD, is a physician-scientist dedicated to advancing the care and treatment of patients with rheumatologic conditions such as rheumatoid arthritis, lupus, psoriatic arthritis, and other autoimmune diseases. She uses her unique backgrounds in Biology, Computer Science, and Clinical Rheumatology to investigate the role of the human gut microbiome in the treatment of rheumatoid arthritis. She uses an innovative combination of patient specimens, microbiology, next generation sequencing, and gnotobiotic mouse models to better understand how our microbiome, which many consider our "second genome," influences health and disease.
Education
2017 - Rheumatology, UCSF
2014 - Internal Medicine, UCSF
MD, PhD, 2012 - Genomics, University of Pennsylvania
BA, 2004 - Biology, Swarthmore College
BA, 2004 - Computer Science, Swarthmore College
Publications
  1. Pharmacomicrobiomics in inflammatory arthritis: gut microbiome as modulator of therapeutic response.
  2. Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses.
  3. Mirror, mirror on the wall: which microbiomes will help heal them all?
  4. Stress-induced changes in gene interactions in human cells.
  5. Polymorphic cis- and trans-regulation of human gene expression.
  6. Gene expression and genetic variation in response to endoplasmic reticulum stress in human cells.
  7. Coexpression network based on natural variation in human gene expression reveals gene interactions and functions.